Thesis defense of Lionel LARTIGUE

  • Soutenance de Thèse
  • Evénement scientifique
schéma de polymères à empreinte ionique (IIP)

 

Thesis defense of Lionel LARTIGUE, PhD student in the Biophotonics group of the Laboratoire Charles Fabry, on 16 January 2023 at 2pm in the Auditorium of the Institut d'Optique in Palaiseau, on the topic: "Development and validation of an in situ surface plasmon resonance imaging system for the determination of metallic elements in freshwater and marine environments."

Abstract: "Metallic ions coming from natural sources or antropogenic activities are present in the Earth waters from phreatic tables to deep oceans. Their influence on the biotopes and the human health, even at very low concentrations, is actively studied. So far, most of the analyzes are done in laboratories and there is a necessity to develop an in-situ sensor to provide a in-field means of monitoring.

Surface Plasmon Resonance (SPR) based sensors are widely used in the biodetection field for the monitoring of chemical species at concentration as low as nanomolar. The most common type of SPR sensors is based on the measure of the reflectivity variations, of a 50 nm thick gold film, when a target chemical specie is captured by molecular probes grafted on the gold surface.
 
In order to detect metallic ions, Ion Imprinted Polymers~(IIP) have been chosen as specific molecular probes. The IIP specificity to imprinted ions comes from both electrostatic interaction and the geometry of specific cavities frozen in the polymer matrix. A method has been developped to synthetize and to graft these polymers as thin films on the gold surface and to control their thickness at the nanometric scale. Detection of copper and zinc has been achieved at concentrations as low as about 500~nM in controlled samples and in a laboratory environment."
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